| ncRNA name | hsa-miR-15b |
| ncRNA Category | miRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Homo sapiens |
| Tissues/Cell_line | human retinal endothelial cells (HRECs) |
| Methods | transfection, qRT-PCR, Western blot, ELISA |
| Expression pattern | down-regulated |
| Functional description | miR-15b and miR-16 play a role in the inhibition of insulin resistance via reduced TNFα and SOCS3 signaling and increased IGFBP-3 levels, resulting in REC protection from hyperglycemia-induced apoptosis. |
| PubMed ID | 25888955 |
| Year | 2015 |
| Title | miR-15b/16 protects primary human retinal microvascular endothelial cells against hyperglycemia-induced increases in tumor necrosis factor alpha and suppressor of cytokine signaling 3. |
| Drug-related ncRNA | NO |
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